Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration

Environmental factors, including pesticides, have been linked to autism and neurodegeneration risk using retrospective epidemiological studies. Here we sought to prospectively identify chemicals that share transcriptomic signatures with neurological disorders, by exposing mouse cortical neuron-enric...

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Detalles Bibliográficos
Autores principales: Pearson, Brandon L., Simon, Jeremy M., McCoy, Eric S., Salazar, Gabriela, Fragola, Giulia, Zylka, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821887/
https://www.ncbi.nlm.nih.gov/pubmed/27029645
http://dx.doi.org/10.1038/ncomms11173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821887/
https://www.ncbi.nlm.nih.gov/pubmed/27029645
http://dx.doi.org/10.1038/ncomms11173

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