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Methylation Status of SP1 Sites within miR-23a-27a-24-2 Promoter Region Influences Laryngeal Cancer Cell Proliferation and Apoptosis

DNA methylation plays critical roles in regulation of microRNA expression and function. miR-23a-27a-24-2 cluster has various functions and aberrant expression of the cluster is a common event in many cancers. However, whether DNA methylation influences the cluster expression and function is not repo...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Zhang, Zhao-Xiong, Chen, Sheng, Qiu, Guang-Bin, Xu, Zhen-Ming, Fu, Wei-Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821919/
https://www.ncbi.nlm.nih.gov/pubmed/27099864
http://dx.doi.org/10.1155/2016/2061248