Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats

Dopamine D2 receptors (D2R) in the medial prefrontal cortex (mPFC) are key players in the etiology and therapeutics of schizophrenia. The overactivation of these receptors contributes to mPFC dysfunction. Chronic treatment with D2R agonists modifies the expression of molecules implicated in neuronal...

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Detalles Bibliográficos
Autores principales: Castillo-Gómez, Esther, Varea, Emilio, Blasco-Ibáñez, José Miguel, Crespo, Carlos, Nacher, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821975/
https://www.ncbi.nlm.nih.gov/pubmed/27110404
http://dx.doi.org/10.1155/2016/1615363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821975/
https://www.ncbi.nlm.nih.gov/pubmed/27110404
http://dx.doi.org/10.1155/2016/1615363

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