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Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development

How lineage specifiers are regulated during development is an outstanding question, and the molecular regulation of osteogenic factor RUNX2 remains to be fully understood. Here we report that the Mediator subunit MED23 cooperates with RUNX2 to regulate osteoblast differentiation and bone development...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Yao, Xiao, Yan, Guang, Xu, YiChi, Yan, Jun, Zou, Weiguo, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821994/
https://www.ncbi.nlm.nih.gov/pubmed/27033977
http://dx.doi.org/10.1038/ncomms11149