Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening

Establishment and maintenance of apico-basal polarity in epithelial organs must be tightly coupled with cell division, but the underlying molecular mechanisms are largely unknown. Using 3D cultures of renal MDCK cells (cysts), we found that the Rab35 GTPase plays a crucial role in polarity initiatio...

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Detalles Bibliográficos
Autores principales: Klinkert, Kerstin, Rocancourt, Murielle, Houdusse, Anne, Echard, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822036/
https://www.ncbi.nlm.nih.gov/pubmed/27040773
http://dx.doi.org/10.1038/ncomms11166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822036/
https://www.ncbi.nlm.nih.gov/pubmed/27040773
http://dx.doi.org/10.1038/ncomms11166

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