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Chronic cerebral hypoperfusion enhances Tau hyperphosphorylation and reduces autophagy in Alzheimer’s disease mice

Cerebral hypoperfusion and impaired autophagy are two etiological factors that have been identified as being associated with the development of Alzheimer’s disease (AD). Nevertheless, the exact relationships among these pathological processes remain unknown. To elucidate the impact of cerebral hypop...

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Detalles Bibliográficos
Autores principales: Qiu, Lifeng, Ng, Gandi, Tan, Eng King, Liao, Ping, Kandiah, Nagaendran, Zeng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822118/
https://www.ncbi.nlm.nih.gov/pubmed/27050297
http://dx.doi.org/10.1038/srep23964