E2 enzymes: more than just middle men

Ubiquitin-conjugating enzymes (E2s) are the central players in the trio of enzymes responsible for the attachment of ubiquitin (Ub) to cellular proteins. Humans have ∼40 E2s that are involved in the transfer of Ub or Ub-like (Ubl) proteins (e.g., SUMO and NEDD8). Although the majority of E2s are onl...

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Detalles Bibliográficos
Autores principales: Stewart, Mikaela D, Ritterhoff, Tobias, Klevit, Rachel E, Brzovic, Peter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822130/
https://www.ncbi.nlm.nih.gov/pubmed/27002219
http://dx.doi.org/10.1038/cr.2016.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822130/
https://www.ncbi.nlm.nih.gov/pubmed/27002219
http://dx.doi.org/10.1038/cr.2016.35

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