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Substrate specificity of the ubiquitin and Ubl proteases

Conjugation and deconjugation of ubiquitin and ubiquitin-like proteins (Ubls) to cellular proteins are highly regulated processes integral to cellular homeostasis. Most often, the C-termini of these small polypeptides are attached to lysine side chains of target proteins by an amide (isopeptide) lin...

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Detalles Bibliográficos
Autores principales: Ronau, Judith A, Beckmann, John F, Hochstrasser, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822132/
https://www.ncbi.nlm.nih.gov/pubmed/27012468
http://dx.doi.org/10.1038/cr.2016.38