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Targeted mutagenesis in chicken using CRISPR/Cas9 system

The CRISPR/Cas9 system is a simple and powerful tool for genome editing in various organisms including livestock animals. However, the system has not been applied to poultry because of the difficulty in accessing their zygotes. Here we report the implementation of CRISPR/Cas9-mediated gene targeting...

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Detalles Bibliográficos
Autores principales: Oishi, Isao, Yoshii, Kyoko, Miyahara, Daichi, Kagami, Hiroshi, Tagami, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822141/
https://www.ncbi.nlm.nih.gov/pubmed/27050479
http://dx.doi.org/10.1038/srep23980