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Ndfip2 is a potential regulator of the iron transporter DMT1 in the liver

The regulation of divalent metal ion transporter DMT1, the primary non-heme iron importer in mammals, is critical for maintaining iron homeostasis. Previously we identified ubiquitin-dependent regulation of DMT1 involving the Nedd4 family of ubiquitin ligases and the Ndfip1 and Ndfip2 adaptors. We a...

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Detalles Bibliográficos
Autores principales: Foot, Natalie J., Gembus, Kelly M., Mackenzie, Kimberly, Kumar, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822147/
https://www.ncbi.nlm.nih.gov/pubmed/27048792
http://dx.doi.org/10.1038/srep24045