Development, validation and quantitative assessment of an enzymatic assay suitable for small molecule screening and profiling: A case-study

The successful discovery and subsequent development of small molecule inhibitors of drug targets relies on the establishment of robust, cost-effective, quantitative, and physiologically relevant in vitro assays that can support prolonged screening and optimization campaigns. The current study illust...

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Detalles Bibliográficos
Autores principales: Sancenon, Vicente, Goh, Wei Hau, Sundaram, Aishwarya, Er, Kai Shih, Johal, Nidhi, Mukhina, Svetlana, Carr, Grant, Dhakshinamoorthy, Saravanakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822204/
https://www.ncbi.nlm.nih.gov/pubmed/27077032
http://dx.doi.org/10.1016/j.bdq.2015.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822204/
https://www.ncbi.nlm.nih.gov/pubmed/27077032
http://dx.doi.org/10.1016/j.bdq.2015.03.001

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