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Development, validation and quantitative assessment of an enzymatic assay suitable for small molecule screening and profiling: A case-study
The successful discovery and subsequent development of small molecule inhibitors of drug targets relies on the establishment of robust, cost-effective, quantitative, and physiologically relevant in vitro assays that can support prolonged screening and optimization campaigns. The current study illust...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822204/ https://www.ncbi.nlm.nih.gov/pubmed/27077032 http://dx.doi.org/10.1016/j.bdq.2015.03.001 |