Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death

BACKGROUND: Bone morphogenetic proteins (BMP) are embryonic proteins that are part of the transforming growth factor (TGFβ) superfamily, which are aberrantly expressed in many carcinomas. Inhibition of BMP receptors with small molecule inhibitors decreases growth and induces death of lung cancer cel...

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Detalles Bibliográficos
Autores principales: Augeri, Dave J., Langenfeld, Elaine, Castle, Monica, Gilleran, John A., Langenfeld, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822253/
https://www.ncbi.nlm.nih.gov/pubmed/27048361
http://dx.doi.org/10.1186/s12943-016-0511-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822253/
https://www.ncbi.nlm.nih.gov/pubmed/27048361
http://dx.doi.org/10.1186/s12943-016-0511-9

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