Cargando…

Learning defects in Drosophila growth restricted chico mutants are caused by attenuated adenylyl cyclase activity

BACKGROUND: Reduced insulin/insulin-like growth factor signaling (IIS) is a major cause of symmetrical intrauterine growth retardation (IUGR), an impairment in cell proliferation during prenatal development that results in global growth defects and mental retardation. In Drosophila, chico encodes th...

Descripción completa

Detalles Bibliográficos
Autores principales: Naganos, Shintaro, Ueno, Kohei, Horiuchi, Junjiro, Saitoe, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822261/
https://www.ncbi.nlm.nih.gov/pubmed/27048332
http://dx.doi.org/10.1186/s13041-016-0217-3