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Learning defects in Drosophila growth restricted chico mutants are caused by attenuated adenylyl cyclase activity
BACKGROUND: Reduced insulin/insulin-like growth factor signaling (IIS) is a major cause of symmetrical intrauterine growth retardation (IUGR), an impairment in cell proliferation during prenatal development that results in global growth defects and mental retardation. In Drosophila, chico encodes th...
Autores principales: | Naganos, Shintaro, Ueno, Kohei, Horiuchi, Junjiro, Saitoe, Minoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822261/ https://www.ncbi.nlm.nih.gov/pubmed/27048332 http://dx.doi.org/10.1186/s13041-016-0217-3 |
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