Cargando…

Intrinsic Contribution of Perforin to NK-Cell Homeostasis during Mouse Cytomegalovirus Infection

In addition to their role as effector cells in virus control, natural killer (NK) cells have an immunoregulatory function in shaping the antiviral T-cell response. This function is further pronounced in perforin-deficient mice that show the enhanced NK-cell proliferation and cytokine secretion upon...

Descripción completa

Detalles Bibliográficos
Autores principales: Arapović, Maja, Brizić, Ilija, Popović, Branka, Jurković, Slaven, Jordan, Stefan, Krmpotić, Astrid, Arapović, Jurica, Jonjić, Stipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822405/
https://www.ncbi.nlm.nih.gov/pubmed/27092144
http://dx.doi.org/10.3389/fimmu.2016.00133