Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

Oncolytic viruses (OVs) are unique anticancer agents based on their pleotropic modes of action, which include, besides viral tumor cell lysis, activation of antitumor immunity. A panel of diverse viruses, often genetically engineered, has advanced to clinical investigation, including phase 3 studies...

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Detalles Bibliográficos
Autores principales: Ungerechts, Guy, Bossow, Sascha, Leuchs, Barbara, Holm, Per S, Rommelaere, Jean, Coffey, Matt, Coffin, Rob, Bell, John, Nettelbeck, Dirk M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822647/
https://www.ncbi.nlm.nih.gov/pubmed/27088104
http://dx.doi.org/10.1038/mtm.2016.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822647/
https://www.ncbi.nlm.nih.gov/pubmed/27088104
http://dx.doi.org/10.1038/mtm.2016.18

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