PhenomeExpress: A refined network analysis of expression datasets by inclusion of known disease phenotypes

We describe a new method, PhenomeExpress, for the analysis of transcriptomic datasets to identify pathogenic disease mechanisms. Our analysis method includes input from both protein-protein interaction and phenotype similarity networks. This introduces valuable information from disease relevant phen...

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Detalles Bibliográficos
Autores principales: Soul, Jamie, Hardingham, Timothy E., Boot-Handford, Raymond P., Schwartz, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822650/
https://www.ncbi.nlm.nih.gov/pubmed/25631385
http://dx.doi.org/10.1038/srep08117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822650/
https://www.ncbi.nlm.nih.gov/pubmed/25631385
http://dx.doi.org/10.1038/srep08117

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