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PhenomeExpress: A refined network analysis of expression datasets by inclusion of known disease phenotypes
We describe a new method, PhenomeExpress, for the analysis of transcriptomic datasets to identify pathogenic disease mechanisms. Our analysis method includes input from both protein-protein interaction and phenotype similarity networks. This introduces valuable information from disease relevant phen...
Autores principales: | Soul, Jamie, Hardingham, Timothy E., Boot-Handford, Raymond P., Schwartz, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822650/ https://www.ncbi.nlm.nih.gov/pubmed/25631385 http://dx.doi.org/10.1038/srep08117 |
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