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Lysosomal Storage Diseases—Regulating Neurodegeneration

Autophagy is a complex pathway regulated by numerous signaling events that recycles macromolecules and can be perturbed in lysosomal storage diseases (LSDs). The concept of LSDs, which are characterized by aberrant, excessive storage of cellular material in lysosomes, developed following the discove...

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Detalles Bibliográficos
Autores principales: Onyenwoke, Rob U., Brenman, Jay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822725/
https://www.ncbi.nlm.nih.gov/pubmed/27081317
http://dx.doi.org/10.4137/JEN.S25475