Cargando…

Lysosomal Storage Diseases—Regulating Neurodegeneration

Autophagy is a complex pathway regulated by numerous signaling events that recycles macromolecules and can be perturbed in lysosomal storage diseases (LSDs). The concept of LSDs, which are characterized by aberrant, excessive storage of cellular material in lysosomes, developed following the discove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onyenwoke, Rob U., Brenman, Jay E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822725/ https://www.ncbi.nlm.nih.gov/pubmed/27081317 http://dx.doi.org/10.4137/JEN.S25475

Ejemplares similares

Isolation of AMP-activated protein kinase (AMPK) alleles required for neuronal maintenance in Drosophila melanogaster
por: Swick, Lance L., et al.
Publicado: (2013)

AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis
por: Onyenwoke, Rob U., et al.
Publicado: (2012)

The mucolipidosis IV Ca(2+) channel TRPML1 (MCOLN1) is regulated by the TOR kinase
por: Onyenwoke, Rob U., et al.
Publicado: (2015)

Lysosomes and Lysosomal Storage Diseases
por: Noebels, Jeffrey L.
Publicado: (1981)

Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases
por: Sambri, Irene, et al.
Publicado: (2016)

Lysosomal storage diseases
por: Ferreira, Carlos R., et al.
Publicado: (2017)

Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration
por: Osellame, L D, et al.
Publicado: (2014)

Biomarkers in Lysosomal Storage Diseases
por: Bobillo Lobato, Joaquin, et al.
Publicado: (2016)

Lysosomal Functions in Glia Associated with Neurodegeneration
por: Kreher, Conlan, et al.
Publicado: (2021)

Autophagy in lysosomal storage disorders
por: Lieberman, Andrew P., et al.
Publicado: (2012)

Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer
por: Dermaut, Bart, et al.
Publicado: (2005)

Therapeutic Approaches in Lysosomal Storage Diseases
por: Fernández-Pereira, Carlos, et al.
Publicado: (2021)

Lysosomal Storage Disorders Shed Light on Lysosomal Dysfunction in Parkinson’s Disease
por: Blumenreich, Shani, et al.
Publicado: (2020)

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
por: Platt, Frances M., et al.
Publicado: (2012)

Potential Treatment of Lysosomal Storage Disease through Modulation of the Mitochondrial—Lysosomal Axis
por: Kuk, Myeong Uk, et al.
Publicado: (2021)

Highlights on Genomics Applications for Lysosomal Storage Diseases
por: La Cognata, Valentina, et al.
Publicado: (2020)

The rapidly evolving view of lysosomal storage diseases
por: Parenti, Giancarlo, et al.
Publicado: (2021)

Lysosomal positioning diseases: beyond substrate storage
por: Scerra, Gianluca, et al.
Publicado: (2022)

Calcium Signaling Derangement and Disease Development and Progression
por: Sivaraman, Vijay, et al.
Publicado: (2021)

Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes
por: Wong, Ching-On
Publicado: (2020)

Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration
por: Kos, Janko, et al.
Publicado: (2022)

Altered Metabolism and Persistent Starvation Behaviors Caused by Reduced AMPK Function in Drosophila
por: Johnson, Erik C., et al.
Publicado: (2010)

Lysosomal Storage Disorders and Malignancy
por: Pastores, Gregory M., et al.
Publicado: (2017)

A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline
por: Hindle, Samantha J., et al.
Publicado: (2017)

Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases
por: Keeling, Kim M.
Publicado: (2016)

Molecular Pathways and Respiratory Involvement in Lysosomal Storage Diseases
por: Faverio, Paola, et al.
Publicado: (2019)

Sphingolipid lysosomal storage diseases: from bench to bedside
por: Abed Rabbo, Muna, et al.
Publicado: (2021)

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration
por: Hu, Yong-Bo, et al.
Publicado: (2015)

Neuroinflammatory paradigms in lysosomal storage diseases
por: Bosch, Megan E., et al.
Publicado: (2015)

Mitochondrial Dysfunction in Lysosomal Storage Disorders
por: de la Mata, Mario, et al.
Publicado: (2016)

Calcium-Dependent Pulmonary Inflammation and Pharmacological Interventions and Mediators
por: Shipman, Jeffrey G., et al.
Publicado: (2021)

Clinical studies in lysosomal storage diseases: Past, present, and future
por: Boudes, Pol F
Publicado: (2013)

From Lysosomal Storage Diseases to NKT Cell Activation and Back
por: Pereira, Cátia S., et al.
Publicado: (2017)

Pompe Disease: New Developments in an Old Lysosomal Storage Disorder
por: Meena, Naresh K., et al.
Publicado: (2020)

Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration
por: Quick, Joseph D., et al.
Publicado: (2023)

Modeling Lysosomal Storage Diseases in the Zebrafish
por: Zhang, T., et al.
Publicado: (2020)

Metabolism of Glycosphingolipids and Their Role in the Pathophysiology of Lysosomal Storage Disorders
por: Ryckman, Alex E., et al.
Publicado: (2020)

Lysosomal storage disorders
por: Cabrera-Salazar, Mario A, et al.
Publicado: (2007)

Factors and processes modulating phenotypes in neuronopathic lysosomal storage diseases
por: Jakóbkiewicz-Banecka, Joanna, et al.
Publicado: (2013)

Dysregulation of autophagy as a common mechanism in lysosomal storage diseases
por: Seranova, Elena, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_do2q4j88c1kr9h5j75kitffomq