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Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication
DNA Polymerases generate pyrophosphate every time they catalyze a step of DNA elongation. This elongation reaction is generally believed as thermodynamically favoured by the hydrolysis of pyrophosphate, catalyzed by inorganic pyrophosphatases. However, the specific action of inorganic pyrophosphatas...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822814/ https://www.ncbi.nlm.nih.gov/pubmed/27050298 http://dx.doi.org/10.1371/journal.pone.0152915 |