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Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication

DNA Polymerases generate pyrophosphate every time they catalyze a step of DNA elongation. This elongation reaction is generally believed as thermodynamically favoured by the hydrolysis of pyrophosphate, catalyzed by inorganic pyrophosphatases. However, the specific action of inorganic pyrophosphatas...

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Detalles Bibliográficos
Autores principales:	Lapenta, Fabio, Montón Silva, Alejandro, Brandimarti, Renato, Lanzi, Massimiliano, Gratani, Fabio Lino, Vellosillo Gonzalez, Perceval, Perticarari, Sofia, Hochkoeppler, Alejandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822814/ https://www.ncbi.nlm.nih.gov/pubmed/27050298 http://dx.doi.org/10.1371/journal.pone.0152915

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