An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice

Interferon regulatory factor 5 (IRF5) has been called a “master switch” for its ability to determine whether cells mount proinflammatory or anti-inflammatory responses. Accordingly, IRF5 should be an attractive target for therapeutic drug development. Here we report on the development of a novel dec...

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Detalles Bibliográficos
Autores principales: Weihrauch, Dorothee, Krolikowski, John G., Jones, Deron W., Zaman, Tahniyath, Bamkole, Omoshalewa, Struve, Janine, Pillai, Savin, Pagel, Paul S., Lohr, Nicole L., Pritchard, Kirkwood A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822818/
https://www.ncbi.nlm.nih.gov/pubmed/27050551
http://dx.doi.org/10.1371/journal.pone.0151999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822818/
https://www.ncbi.nlm.nih.gov/pubmed/27050551
http://dx.doi.org/10.1371/journal.pone.0151999

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