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Discrepant Results of Experimental Human Mesenchymal Stromal Cell Therapy after Myocardial Infarction: Are Animal Models Robust Enough?

BACKGROUND: Human mesenchymal stromal cells (MSCs) have been reported to preserve cardiac function in myocardial infarction (MI) models. Previously, we found a beneficial effect of intramyocardial injection of unstimulated human MSCs (uMSCs) on cardiac function after permanent coronary artery ligati...

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Detalles Bibliográficos
Autores principales: den Haan, Melina C., van Zuylen, Vanessa-Leigh, Pluijmert, Niek J., Schutte, Cindy I., Fibbe, Willem E., Schalij, Martin J., Roelofs, Helene, Atsma, Douwe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822837/
https://www.ncbi.nlm.nih.gov/pubmed/27050443
http://dx.doi.org/10.1371/journal.pone.0152938