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Specific Elimination of Latently HIV-1 Infected Cells Using HIV-1 Protease-Sensitive Toxin Nanocapsules

Anti-retroviral drugs suppress HIV-1 plasma viremia to undetectable levels; however, latent HIV-1 persists in reservoirs within HIV-1-infected patients. The silent provirus can be activated through the use of drugs, including protein kinase C activators and histone deacetylase inhibitors. This “shoc...

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Detalles Bibliográficos
Autores principales: Wen, Jing, Yan, Ming, Liu, Yang, Li, Jie, Xie, Yiming, Lu, Yunfeng, Kamata, Masakazu, Chen, Irvin S. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822841/
https://www.ncbi.nlm.nih.gov/pubmed/27049645
http://dx.doi.org/10.1371/journal.pone.0151572