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Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes

Cellular receptors usually contain a designated sensory domain that recognizes the signal. Per/Arnt/Sim (PAS) domains are ubiquitous sensors in thousands of species ranging from bacteria to humans. Although PAS domains were described as intracellular sensors, recent structural studies revealed PAS-l...

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Detalles Bibliográficos
Autores principales: Upadhyay, Amit A., Fleetwood, Aaron D., Adebali, Ogun, Finn, Robert D., Zhulin, Igor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822843/
https://www.ncbi.nlm.nih.gov/pubmed/27049771
http://dx.doi.org/10.1371/journal.pcbi.1004862