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Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors

Treatments for retinoblastoma (Rb) vary depending on the size and location of the intraocular lesions and include chemotherapy and radiation therapy. We examined whether agents used to treat Rb induce a pro-survival phenotype associated with increased expression of survivin, a member of the inhibito...

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Detalles Bibliográficos
Autores principales: Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Lederman, Ariel, Kim, Jonathan, Gomer, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822873/
https://www.ncbi.nlm.nih.gov/pubmed/27050416
http://dx.doi.org/10.1371/journal.pone.0153011