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Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors
Treatments for retinoblastoma (Rb) vary depending on the size and location of the intraocular lesions and include chemotherapy and radiation therapy. We examined whether agents used to treat Rb induce a pro-survival phenotype associated with increased expression of survivin, a member of the inhibito...
Autores principales: | Ferrario, Angela, Luna, Marian, Rucker, Natalie, Wong, Sam, Lederman, Ariel, Kim, Jonathan, Gomer, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822873/ https://www.ncbi.nlm.nih.gov/pubmed/27050416 http://dx.doi.org/10.1371/journal.pone.0153011 |
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