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Generation of Large Numbers of Antigen-Expressing Human Dendritic Cells Using CD14-ML Technology

We previously reported a method to expand human monocytes through lentivirus-mediated introduction of cMYC and BMI1, and we named the monocyte-derived proliferating cells, CD14-ML. CD14-ML differentiated into functional DC (CD14-ML-DC) upon addition of IL-4, resulting in the generation of a large nu...

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Detalles Bibliográficos
Autores principales: Imamura, Yuya, Haruta, Miwa, Tomita, Yusuke, Matsumura, Keiko, Ikeda, Tokunori, Yuno, Akira, Hirayama, Masatoshi, Nakayama, Hideki, Mizuta, Hiroshi, Nishimura, Yasuharu, Senju, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822879/
https://www.ncbi.nlm.nih.gov/pubmed/27050553
http://dx.doi.org/10.1371/journal.pone.0152384