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Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study

BACKGROUND: Metabolic abnormalities that lead to type 2 diabetes mellitus begin in early childhood. OBJECTIVES: We investigate whether common genetic variants identified in adults have an effect on glucose in early life. METHODS: 610 newborns, 463 mothers, and 366 fathers were included in the presen...

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Detalles Bibliográficos
Autores principales: Sohani, Zahra N., Anand, Sonia S., Robiou-du-Pont, Sebastien, Morrison, Katherine M., McDonald, Sarah D., Atkinson, Stephanie A., Teo, Koon K., Meyre, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822946/
https://www.ncbi.nlm.nih.gov/pubmed/27049325
http://dx.doi.org/10.1371/journal.pone.0152107