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Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study
BACKGROUND: Metabolic abnormalities that lead to type 2 diabetes mellitus begin in early childhood. OBJECTIVES: We investigate whether common genetic variants identified in adults have an effect on glucose in early life. METHODS: 610 newborns, 463 mothers, and 366 fathers were included in the presen...
Autores principales: | Sohani, Zahra N., Anand, Sonia S., Robiou-du-Pont, Sebastien, Morrison, Katherine M., McDonald, Sarah D., Atkinson, Stephanie A., Teo, Koon K., Meyre, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822946/ https://www.ncbi.nlm.nih.gov/pubmed/27049325 http://dx.doi.org/10.1371/journal.pone.0152107 |
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