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GSK-3α Is a Novel Target of CREB and CREB-GSK-3α Signaling Participates in Cell Viability in Lung Cancer

Overexpression or activation of cyclic AMP-response element-binding protein (CREB) has been known to be involved in several human malignancies, including lung cancer. Genes regulated by CREB have been reported to suppress apoptosis, induce cell proliferation, inflammation, and tumor metastasis. Howe...

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Detalles Bibliográficos
Autores principales: Park, Sin-Aye, Lee, Jong Woo, Herbst, Roy S., Koo, Ja Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822949/
https://www.ncbi.nlm.nih.gov/pubmed/27049759
http://dx.doi.org/10.1371/journal.pone.0153075