Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules

Carboxypeptidase A6 (CPA6) is an extracellular matrix metallocarboxypeptidase that modulates peptide and protein function by removal of hydrophobic C-terminal amino acids. Mutations in the human CPA6 gene that reduce enzymatic activity in the extracellular matrix are associated with febrile seizures...

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Detalles Bibliográficos
Autores principales: Lopes, Mark William, Sapio, Matthew R., Leal, Rodrigo B., Fricker, Lloyd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822968/
https://www.ncbi.nlm.nih.gov/pubmed/27050163
http://dx.doi.org/10.1371/journal.pone.0152905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822968/
https://www.ncbi.nlm.nih.gov/pubmed/27050163
http://dx.doi.org/10.1371/journal.pone.0152905

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