Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiation

Colorectal cancer is the third most frequently diagnosed cancer worldwide. Prevention of colorectal cancer initiation represents the most effective overall strategy to reduce its associated morbidity and mortality. Activating KRAS mutation (KRAS(mut)) is the most prevalent oncogenic driver in colore...

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Detalles Bibliográficos
Autores principales: Le Rolle, Anne-France, Chiu, Thang K., Zeng, Zhaoshi, Shia, Jinru, Weiser, Martin R., Paty, Philip B., Chiu, Vi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823026/
https://www.ncbi.nlm.nih.gov/pubmed/26744320
http://dx.doi.org/10.18632/oncotarget.6818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823026/
https://www.ncbi.nlm.nih.gov/pubmed/26744320
http://dx.doi.org/10.18632/oncotarget.6818

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