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Polo-like kinase 1 mediates BRCA1 phosphorylation and recruitment at DNA double-strand breaks
Accurate repair of DNA double-strand breaks (DSB) caused during DNA replication and by exogenous stresses is critical for the maintenance of genomic integrity. There is growing evidence that the Polo-like kinase 1 (Plk1) that plays a number of pivotal roles in cell proliferation can directly partici...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823034/ https://www.ncbi.nlm.nih.gov/pubmed/26745677 http://dx.doi.org/10.18632/oncotarget.6825 |