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Tumor-associated fibroblast-conditioned medium induces CDDP resistance in HNSCC cells

OBJECTIVE: EMT (epithelial to mesenchymal transition) contributes to tumor progression and metastasis. We aimed to investigate the effects of EMT on CDDP resistance in HNSCC (head and neck squamous cell carcinoma)-cells. METHODS: EMT was induced using conditioned medium from a tumor cell/fibroblast...

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Detalles Bibliográficos
Autores principales: Steinbichler, Teresa Bernadette, Metzler, Veronika, Pritz, Christian, Riechelmann, Herbert, Dudas, Jozsef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823051/
https://www.ncbi.nlm.nih.gov/pubmed/26497215
http://dx.doi.org/10.18632/oncotarget.6210