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Concomitant BET and MAPK blockade for effective treatment of ovarian cancer

Ovarian cancer is the most lethal gynecologic malignancy, and it is imperative to develop new treatments to ameliorate patient survival. Using an anti-cancer drug library containing 180 small molecule inhibitors, we performed a high-content image-based screen and found that BET and MEK inhibitors ar...

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Detalles Bibliográficos
Autores principales: Jing, Ying, Zhang, Zhenfeng, Ma, Pengfei, An, Shimin, Shen, Ying, Zhu, Liang, Zhuang, Guanglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823054/
https://www.ncbi.nlm.nih.gov/pubmed/26575423
http://dx.doi.org/10.18632/oncotarget.6309