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Computational selection of antibody-drug conjugate targets for breast cancer

The selection of therapeutic targets is a critical aspect of antibody-drug conjugate research and development. In this study, we applied computational methods to select candidate targets overexpressed in three major breast cancer subtypes as compared with a range of vital organs and tissues. Microar...

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Detalles Bibliográficos
Autores principales: Fauteux, François, Hill, Jennifer J., Jaramillo, Maria L., Pan, Youlian, Phan, Sieu, Famili, Fazel, O'Connor-McCourt, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823055/
https://www.ncbi.nlm.nih.gov/pubmed/26700623
http://dx.doi.org/10.18632/oncotarget.6679