An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation

Therapy resistance is one of the major impediments to successful cancer treatment. In breast cancer, a small subpopulation of cells with stem cell features, named breast cancer stem cells (BCSC), is responsible for metastasis and recurrence of the tumor. BCSC have the unique ability to grow under no...

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Detalles Bibliográficos
Autores principales: Smit, Linda, Berns, Katrien, Spence, Katherine, Ryder, W. David, Zeps, Nik, Madiredjo, Mandy, Beijersbergen, Roderick, Bernards, René, Clarke, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823058/
https://www.ncbi.nlm.nih.gov/pubmed/26595803
http://dx.doi.org/10.18632/oncotarget.6354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823058/
https://www.ncbi.nlm.nih.gov/pubmed/26595803
http://dx.doi.org/10.18632/oncotarget.6354

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