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Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells

We recently reported that normal hematopoietic stem cells express functional pituitary sex hormone (SexH) receptors. Here we report for the first time that pituitary-secreted gonadotrophins stimulate migration, adhesion, and proliferation of several human myeloid and lymphoid leukemia cell lines. Si...

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Detalles Bibliográficos
Autores principales: Abdelbaset-Ismail, Ahmed, Borkowska, Sylwia, Janowska-Wieczorek, Anna, Tonn, Torsten, Rodriguez, Cesar, Moniuszko, Marcin, Bolkun, Lukasz, Koloczko, Janusz, Eljaszewicz, Andrzej, Ratajczak, Janina, Ratajczak, Mariusz Z., Kucia, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823088/
https://www.ncbi.nlm.nih.gov/pubmed/26701888
http://dx.doi.org/10.18632/oncotarget.6698