Cargando…

Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells

We recently reported that normal hematopoietic stem cells express functional pituitary sex hormone (SexH) receptors. Here we report for the first time that pituitary-secreted gonadotrophins stimulate migration, adhesion, and proliferation of several human myeloid and lymphoid leukemia cell lines. Si...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdelbaset-Ismail, Ahmed, Borkowska, Sylwia, Janowska-Wieczorek, Anna, Tonn, Torsten, Rodriguez, Cesar, Moniuszko, Marcin, Bolkun, Lukasz, Koloczko, Janusz, Eljaszewicz, Andrzej, Ratajczak, Janina, Ratajczak, Mariusz Z., Kucia, Magda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823088/ https://www.ncbi.nlm.nih.gov/pubmed/26701888 http://dx.doi.org/10.18632/oncotarget.6698

Ejemplares similares

Human haematopoietic stem/progenitor cells express several functional sex hormone receptors
por: Abdelbaset‐Ismail, Ahmed, et al.
Publicado: (2015)

Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1
por: Abdelbaset-Ismail, A, et al.
Publicado: (2017)

Bioactive Phospholipids Enhance Migration and Adhesion of Human Leukemic Cells by Inhibiting Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS) in a p38 MAPK-Dependent Manner
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2018)

Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts
por: Ratajczak, Mariusz Z, et al.
Publicado: (2015)

Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow
por: Adamiak, Mateusz, et al.
Publicado: (2015)

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML
por: Valent, Peter, et al.
Publicado: (2019)

Pituitary sex hormones enhance the pro-metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase-1
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2016)

Pituitary sex hormones enhance the pro-metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase-1
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2019)

PLASMA SPHINGOSINE 1-PHOSPHATE IS A MAJOR CHEMOATTRACTANT THAT DIRECTS EGRESS OF HEMATOPOIETIC STEM PROGENITOR CELLS FROM BONE MARROW AND ITS LEVEL IN PERIPHERAL BLOOD INCREASES DURING MOBILIZATION DUE TO ACTIVATION OF COMPLEMENT CASCADE/MEMBRANE ATTACK COMPLEX
por: Ratajczak, Mariusz Z., et al.
Publicado: (2010)

Heme Oxygenase 1 (HO-1) as an Inhibitor of Trafficking of Normal and Malignant Hematopoietic Stem Cells – Clinical and Translational Implications
por: Ratajczak, Mariusz Z., et al.
Publicado: (2020)

The Expanding Family of Bone Marrow Homing Factors for Hematopoietic Stem Cells: Stromal Derived Factor 1 Is Not the Only Player in the Game
por: Ratajczak, Mariusz Z., et al.
Publicado: (2012)

Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms
por: Ratajczak, Mariusz Z., et al.
Publicado: (2018)

Correction: Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms
por: Ratajczak, Mariusz Z., et al.
Publicado: (2019)

The Nox2-ROS-Nlrp3 Inflammasome Signaling Stimulates in the Hematopoietic Stem/Progenitor Cells Lipogenesis to Facilitate Membrane Lipid Raft Formation
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2022)

External Liver-Derived Complement and Intrinsic Present in Hematopoietic Stem/Progenitor Cells Complosome Modulate Cell Metabolism and Response to Stress
por: Thapa, Arjun, et al.
Publicado: (2023)

A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner?
por: Ratajczak, Mariusz Z., et al.
Publicado: (2010)

The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine
por: Adamiak, Mateusz, et al.
Publicado: (2019)

Toll-like receptor signaling-deficient mice are easy mobilizers: evidence that TLR signaling prevents mobilization of hematopoietic stem/progenitor cells in HO-1-dependent manner
por: Adamiak, M, et al.
Publicado: (2016)

Stem Cells as Potential Therapeutics and Targets for Infection by COVID19 – Special Issue on COVID19 in Stem Cell Reviews and Reports
por: Ratajczak, Mariusz Z., et al.
Publicado: (2021)

HO-1 inhibits migration of leukemic cells
por: Ratajczak, Mariusz Z.
Publicado: (2017)

Extracellular Adenosine (eAdo) - A(2B) Receptor Axis Inhibits in Nlrp3 Inflammasome-dependent Manner Trafficking of Hematopoietic Stem/progenitor Cells
por: Thapa, Arjun, et al.
Publicado: (2022)

Novel evidence that an alternative complement cascade pathway is involved in optimal mobilization of hematopoietic stem/progenitor cells in Nlrp3 inflammasome-dependent manner
por: Adamiak, Mateusz, et al.
Publicado: (2019)

Evidence that a lipolytic enzyme—hematopoietic-specific phospholipase C-β2—promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes
por: Adamiak, M, et al.
Publicado: (2016)

Intracellular complement (complosome) is expressed in hematopoietic stem/progenitor cells (HSPCs) and regulates cell trafficking, metabolism and proliferation in an intracrine Nlrp3 inflammasome-dependent manner
por: Ratajczak, Mariusz Z., et al.
Publicado: (2023)

The “Mystery Cell Population” Residing in Murine Bone Marrow – A Missing Link Between Very Small Embryonic Like Stem Cells and Hematopoietic Stem Cells?
por: Bujko, Kamila, et al.
Publicado: (2023)

Sphingosine-1-phosphate-Mediated Mobilization of Hematopoietic Stem/Progenitor Cells during Intravascular Hemolysis Requires Attenuation of SDF-1-CXCR4 Retention Signaling in Bone Marrow
por: Mierzejewska, Kasia, et al.
Publicado: (2013)

Evidence that the population of quiescent bone marrow-residing very small embryonic/epiblast-like stem cells (VSELs) expands in response to neurotoxic treatment
por: Grymula, Katarzyna, et al.
Publicado: (2014)

SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine “storm” and risk factor for damage of hematopoietic stem cells
por: Ratajczak, Mariusz Z., et al.
Publicado: (2020)

Very small embryonic/epiblast-like stem cells (VSELs) and their potential role in aging and organ rejuvenation – an update and comparison to other primitive small stem cells isolated from adult tissues
por: Ratajczak, Mariusz Z., et al.
Publicado: (2012)

Extracellular Adenosine Triphosphate (eATP) and Its Metabolite, Extracellular Adenosine (eAdo), as Opposing “Yin–Yang” Regulators of Nlrp3 Inflammasome in the Trafficking of Hematopoietic Stem/Progenitor Cells
por: Ratajczak, Mariusz Z., et al.
Publicado: (2021)

Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes
por: Fan, Teresa WM, et al.
Publicado: (2008)

Involvement of BAFF and APRIL in Resistance to Apoptosis of Acute Myeloid Leukemia
por: Bolkun, Lukasz, et al.
Publicado: (2016)

Evidence for induction of a tumor metastasis-receptive microenvironment for ovarian cancer cells in bone marrow and other organs as an unwanted and underestimated side effect of chemotherapy/radiotherapy
por: Gunjal, Pranesh M, et al.
Publicado: (2015)

Danger-associated molecular pattern molecules take unexpectedly a central stage in Nlrp3 inflammasome–caspase-1-mediated trafficking of hematopoietic stem/progenitor cells
por: Thapa, Arjun, et al.
Publicado: (2021)

Expression of the erythropoietin receptor by germline-derived cells - further support for a potential developmental link between the germline and hematopoiesis
por: Suszynska, Malwina, et al.
Publicado: (2014)

Genome-wide analysis of murine bone marrow-derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells
por: MIERZEJEWSKA, KATARZYNA, et al.
Publicado: (2013)

Novel Epigeneitc Mechanisms that Control Pluripotency and Quiescence of Adult Bone Marrow-Derived Oct4(+) Very Small Embryonic Like Stem Cells
por: Shin, Dong-Myung, et al.
Publicado: (2009)

Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?
por: Ratajczak, Mariusz Z., et al.
Publicado: (2016)

The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis
por: Ratajczak, Mariusz Z., et al.
Publicado: (2018)

MOBILIZATION STUDIES IN COMPLEMENT-DEFICIENT MICE REVEAL THAT OPTIMAL AMD3100 MOBILIZATION OF HEMATOPOIETIC STEM CELLS DEPENDS ON COMPLEMENT CASCADE ACTIVATION BY AMD3100-STIMULATED GRANULOCYTES
por: Lee, HakMo, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_i3v9p8df22nm8iuvtu83r5gar2