Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis

AKT is a serine-threonine kinase that becomes hyperactivated in a number of cancers including lung cancer. Based on AKT's association with malignancy, molecules targeting AKT have entered clinical trials for solid tumors including lung cancer. However, the AKT inhibitors being evaluated in clin...

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Detalles Bibliográficos
Autores principales: Franks, S. Elizabeth, Briah, Ritesh, Jones, Robert A., Moorehead, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823107/
https://www.ncbi.nlm.nih.gov/pubmed/26654940
http://dx.doi.org/10.18632/oncotarget.6489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823107/
https://www.ncbi.nlm.nih.gov/pubmed/26654940
http://dx.doi.org/10.18632/oncotarget.6489

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