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Inhibition of EZH2 by chemo- and radiotherapy agents and small molecule inhibitors induces cell death in castration-resistant prostate cancer

Androgen deprivation therapy is the mainstay of treatment of advanced prostate cancer (PCa). However, a significant portion of patients experience disease relapse and tumors ultimately evolve into castration resistant prostate cancer (CRPC), for which there is no cure in the clinic. The Polycomb pro...

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Detalles Bibliográficos
Autores principales: Wu, Changping, Jin, Xin, Yang, Jing, Yang, Yinhui, He, Yundong, Ding, Liya, Pan, Yunqian, Chen, Shuai, Jiang, Jingting, Huang, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823118/
https://www.ncbi.nlm.nih.gov/pubmed/26657505
http://dx.doi.org/10.18632/oncotarget.6497