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Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma

The resistance of apoptosis in cancer cells is pivotal for their survival and is typically ruled by mutations or dysregulation of core apoptotic cascade. Mantle cell lymphoma (MCL) is a non-Hodgkin's B-cell malignancy expressing higher anti-apoptotic proteins providing survival advantage. B-PAC...

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Detalles Bibliográficos
Autores principales: Sarkar, Aloke, Balakrishnan, Kumudha, Chen, Jefferson, Patel, Viralkumar, Neelapu, Sattva S., McMurray, John S., Gandhi, Varsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823120/
https://www.ncbi.nlm.nih.gov/pubmed/26658105
http://dx.doi.org/10.18632/oncotarget.6505