Cargando…

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway

Gamabufotalin (CS-6), a main active compound isolated from Chinese medicine Chansu, has been shown to strongly inhibit cancer cell growth and inflammatory response. However, its effects on angiogenesis have not been known yet. Here, we sought to determine the biological effects of CS-6 on signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Ning, Shi, Lei, Yu, Zhenlong, Dong, Peipei, Wang, Chao, Huo, Xiaokui, Zhang, Baojing, Huang, Shanshan, Deng, Sa, Liu, Kexin, Ma, Tonghui, Wang, Xiaobo, Wu, Lijun, Ma, Xiao-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823125/
https://www.ncbi.nlm.nih.gov/pubmed/26657289
http://dx.doi.org/10.18632/oncotarget.6514