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Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway
Gamabufotalin (CS-6), a main active compound isolated from Chinese medicine Chansu, has been shown to strongly inhibit cancer cell growth and inflammatory response. However, its effects on angiogenesis have not been known yet. Here, we sought to determine the biological effects of CS-6 on signaling...
Autores principales: | Tang, Ning, Shi, Lei, Yu, Zhenlong, Dong, Peipei, Wang, Chao, Huo, Xiaokui, Zhang, Baojing, Huang, Shanshan, Deng, Sa, Liu, Kexin, Ma, Tonghui, Wang, Xiaobo, Wu, Lijun, Ma, Xiao-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823125/ https://www.ncbi.nlm.nih.gov/pubmed/26657289 http://dx.doi.org/10.18632/oncotarget.6514 |
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