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Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

Introduction: Adiponectin (APN), an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II) induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we eval...

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Detalles Bibliográficos
Autores principales: Nour-Eldine, Wared, Ghantous, Crystal M., Zibara, Kazem, Dib, Leila, Issaa, Hawraa, Itani, Hana A., El-Zein, Nabil, Zeidan, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823273/
https://www.ncbi.nlm.nih.gov/pubmed/27092079
http://dx.doi.org/10.3389/fphar.2016.00086