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Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

Membrane transporters play an essential role in the transport of endogenous and exogenous compounds, and consequently they mediate the uptake, distribution, and excretion of many drugs. The clinical relevance of transporters in drug disposition and their effect in adults have been shown in drug–drug...

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Detalles Bibliográficos
Autores principales: Mooij, Miriam G., Nies, Anne T., Knibbe, Catherijne A. J., Schaeffeler, Elke, Tibboel, Dick, Schwab, Matthias, de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823323/
https://www.ncbi.nlm.nih.gov/pubmed/26410689
http://dx.doi.org/10.1007/s40262-015-0328-5