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Advantages and Limitations of Direct PCR Amplification of Bacterial 16S-rDNA from Resected Heart Tissue or Swabs Followed by Direct Sequencing for Diagnosing Infective Endocarditis: A Retrospective Analysis in the Routine Clinical Setting

Infective endocarditis (IE) is a life-threatening disease that is associated with high morbidity and mortality. Its long-term prognosis strongly depends on a timely and optimized antibiotic treatment. Therefore, identification of the causative pathogen is crucial and currently based on blood culture...

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Detalles Bibliográficos
Autores principales: Maneg, Daniela, Sponsel, Janina, Müller, Iris, Lohr, Benedikt, Penders, John, Madlener, Katharina, Hunfeld, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823489/
https://www.ncbi.nlm.nih.gov/pubmed/27110570
http://dx.doi.org/10.1155/2016/7923874